Repeated IVF failure is emotionally exhausting. However, repeated failure does not mean permanent infertility. It signals the need for deeper investigation.

What Is Recurrent Implantation Failure?

Recurrent implantation failure is typically considered after multiple high-quality embryo transfers fail to result in pregnancy.

Implantation depends on:

• Embryo quality

• Uterine lining receptivity

• Hormonal synchronization

• Immune balance

• Genetic compatibility

Failure may result from disruption in any of these areas.

Possible Causes

• Chromosomal abnormalities in embryos

• Thin or poorly receptive endometrial lining

• Chronic endometritis

• Uterine fibroids or polyps

• Immune-related factors

• Thyroid or metabolic disorders

Advanced Diagnostic Tools

Modern fertility centers use:

• Endometrial receptivity assays

• Hysteroscopy

• Preimplantation genetic testing (PGT)

• Doppler blood flow studies

• Immune marker evaluations

Precision-based treatment replaces repetitive cycles.

Why Personalization Improves Success

Standard IVF protocols may not work for everyone. Personalized protocols adjust:

• Stimulation medications

• Embryo transfer timing

• Hormonal supplementation

• Immune modulation

• Lining preparation strategies

The focus shifts from “trying again” to “understanding why.”

Recurrent implantation failure is not about failure. It is about refinement.

When science and personalization combine, outcomes improve.